Topological false discovery rates for brain mapping based on signal height
نویسندگان
چکیده
منابع مشابه
False Discovery Rates
In hypothesis testing, statistical significance is typically based on calculations involving p-values and Type I error rates. A p-value calculated from a single statistical hypothesis test can be used to determine whether there is statistically significant evidence against the null hypothesis. The upper threshold applied to the p-value in making this determination (often 5% in the scientific li...
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Modern scientific technology is providing a new class of large-scale simultaneous inference problems, with hundreds or thousands of hypothesis tests to consider at the same time. Microarrays epitomize this type of technology but similar problems arise in proteomics, time of flight spectroscopy, flow cytometry, FMRI imaging, and massive social science surveys. This paper uses local false discove...
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The problem of multiple testing for the presence of signal in spatial data can involve a large number of locations. Traditionally, each location is tested separately for signal presence but then the findings are reported in terms of clusters of nearby locations. This is an indication that the units of interests for testing are clusters rather than individual locations. The investigator may know...
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This paper extends False Discovery Rates to random fields, where there are uncountably many hypothesis tests. This provides a method for finding local regions in the field where there is a significant signal while controlling either the proportion of area or the number of clusters in which false rejections occur. We develop confidence envelopes for the proportion of false discoveries as a funct...
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When testing a large number of hypotheses, it can be helpful to estimate or control the false discovery rate (FDR), the expected proportion of tests called significant that are truly null. The FDR is intricately linked to probability that a truly null test is significant, and thus a number of methods have been described that estimate or control the FDR by directly using the p-values of the hypo...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2018
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2016.09.045